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The binding ability between shikonin and IL-6. PPI analysis of differential genes (a). The bio-layer interferometry (b), ultrafiltration affinity (c, n = 5), molecular docking (d), and molecular dynamics simulation (e-g) between shikonin and IL-6.

Journal: Journal of Advanced Research

Article Title: Shikonin nasal spray film preparation promoted the repair of nasal mucosal injury by the interaction of shikonin with interleukin-6

doi: 10.1016/j.jare.2025.06.043

Figure Lengend Snippet: The binding ability between shikonin and IL-6. PPI analysis of differential genes (a). The bio-layer interferometry (b), ultrafiltration affinity (c, n = 5), molecular docking (d), and molecular dynamics simulation (e-g) between shikonin and IL-6.

Article Snippet: Recombinant IL-6 protein (cat: HY-P7044 and HY-P7044B) was obtained from MedChemExpress.

Techniques: Binding Assay